Steroids from the Myxobacterium Nannocystis exedens
نویسندگان
چکیده
منابع مشابه
Biosynthesis of phenylnannolone A, a multidrug resistance reversal agent from the halotolerant myxobacterium Nannocystis pusilla B150.
The myxobacterial strain Nannocystis pusilla B150 synthesizes the structurally new polyketides phenylnannolone A–C. Apart from some common volatiles and siderophores, these are the first natural products from the genus Nannocystis. Phenylnannolone A shows inhibitory activity towards the ABCB1 gene product P-glycoprotein and reverses daunorubicin resistance in cancer cells. To decipher the bioch...
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Novel citrate-hydroxamate siderophores, named nannochelins A, B and C, were isolated from the culture broth of the myxobacterium Nannocystis exedens strain Na e485. The new substances showed weak growth-inhibitory activity against some bacteria and fungi.
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Two new secondary metabolites, labindole A [2-methyl-3-(2-nitroethyl)-3H-indole] (1) and labindole B [2-methyl-3-(2-nitrovinyl)-3H-indole] (2), were isolated from the myxobacterium Labilithrixluteola (DSM 27648T). Additionally, four metabolites 3, 4, 5 and 6 already known from other sources were obtained. Their structures were elucidated from high resolution electrospray ionisation mass spectro...
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In 1922 Davis described an infectious disease which was responsible for heavy mortalities in a number of species of warm water fishes in the Mississippi Valley. Although Davis was unsuccessful in his attempts to cultivate the etiological agent, he reported that large numbers of slender, motile bacteria were characteristically present in the lesions of infected fish. He further noted that when m...
متن کاملSalimabromide: unexpected chemistry from the obligate marine myxobacterium Enhygromxya salina.
Marine myxobacteria (Enhygromyxa, Plesiocystis, Pseudoenhygromyxa, Haliangium) are phylogenetically distant from their terrestrial counterparts. Salimabromide is the first natural product from the Plesiocystis/Enhygromyxa clade of obligatory marine myxobacteria. Salimabromide has a new tetracyclic carbon skeleton, comprising a brominated benzene ring, a furano lactone residue, and a cyclohexane...
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ژورنال
عنوان ژورنال: Microbiology
سال: 1983
ISSN: 1350-0872,1465-2080
DOI: 10.1099/00221287-129-6-1629